{"id":1661,"date":"2022-04-03T13:58:07","date_gmt":"2022-04-03T11:58:07","guid":{"rendered":"https:\/\/www.mr-physik.med.fau.de\/?p=1661"},"modified":"2022-12-04T14:20:02","modified_gmt":"2022-12-04T13:20:02","slug":"the-pulseq-cest-standard","status":"publish","type":"post","link":"https:\/\/www.mr-physik.med.fau.de\/en\/2022\/04\/03\/the-pulseq-cest-standard\/","title":{"rendered":"The pulseq-CEST standard"},"content":{"rendered":"<p>Do you know about\u00a0<a href=\"https:\/\/pulseq-cest.github.io\">Pulseq-CEST<\/a>?<br \/>\nPulseq-CEST is a CEST RF preparation standard based on Pulseq initiated by AG Zaiss at FAU, UKER and MPI T\u00fcbingen. You can learn more about Pulseq-CEST in a video by Kai Herz from the MRI Together 2021:<\/p>\n<div class=\"rrze-elements elements-columns cols-3\">\n<div class=\"column colspan-2\">\n<div class=\"rrze-video rrze-video-container has-text-align-left \"><\/p>\n<div class=\"youtube-video plyr-videonum-1\" itemscope itemtype=\"https:\/\/schema.org\/Movie\">\n<meta itemprop=\"name\" content=\"MRI Together 2021 - C1 (Indian) - Open and Reproducible Magnetization-prepared... (K. Herz)\">\n<meta itemprop=\"director\" content=\"ESMRMB\">\n<meta itemprop=\"provider\" content=\"YouTube\">\n<meta itemprop=\"thumbnailUrl\" content=\"https:\/\/i.ytimg.com\/vi\/Uai6Y4eLvfI\/hqdefault.jpg\">\n<meta itemprop=\"version\" content=\"1.0\"><\/p>\n<div class=\"plyr__video-embed\">\n<iframe\n title=\"MRI Together 2021 - C1 (Indian) - Open and Reproducible Magnetization-prepared... (K. Herz)\"\n  src=\"https:\/\/www.youtube-nocookie.com\/embed\/Uai6Y4eLvfI?rel=0&showinfo=0&iv_load_policy=3&modestbranding=1\"\n frameborder=\"0\"\n  allowfullscreen\n  allowtransparency\n  allow=\"autoplay\"\n><\/iframe>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"column colspan-1\"><\/div>\n<\/div>\n\n<p>but also in the original paper <a href=\"https:\/\/doi.org\/10.1002\/mrm.28825\">https:\/\/doi.org\/10.1002\/mrm.28825<\/a><\/p>\n<h3>What is pulseq-CEST?<\/h3>\n<p>First of all, you can define CEST RF preparations in Pulseq-CEST. The definition is done in the machine and human readable Pulseq standard (<a href=\"https:\/\/pulseq.github.io\">https:\/\/pulseq.github.io<\/a>). .<br \/>\nThus, a CEST preparation is finally completely defined, and not just provided by text in the publication.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-509\" src=\"https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pusleq-cest2.png\" alt=\"\" srcset=\"https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pusleq-cest2.png 649w, https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pusleq-cest2-300x232.png 300w, https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pusleq-cest2-310x240.png 310w, https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pusleq-cest2-414x320.png 414w, https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pusleq-cest2-608x470.png 608w\" \/><\/p>\n<p><span class=\"css-901oao css-16my406 r-poiln3 r-bcqeeo r-qvutc0\">You can pull existing <em>author-approved<\/em> pulseq-CEST .seq files from the <\/span><a class=\"css-4rbku5 css-18t94o4 css-901oao css-16my406 r-1cvl2hr r-1loqt21 r-poiln3 r-bcqeeo r-qvutc0\" role=\"link\" href=\"https:\/\/t.co\/U8z80QsljE\" target=\"_blank\" rel=\"noopener noreferrer\"><span class=\"css-901oao css-16my406 r-poiln3 r-hiw28u r-qvk6io r-bcqeeo r-qvutc0\" aria-hidden=\"true\">https:\/\/<\/span>github.com\/kherz\/pulseq-c<span class=\"css-901oao css-16my406 r-poiln3 r-hiw28u r-qvk6io r-bcqeeo r-qvutc0\" aria-hidden=\"true\">est-library<\/span><\/a><span class=\"css-901oao css-16my406 r-poiln3 r-bcqeeo r-qvutc0\"> investigate them, compare them to your approach, and alter them for your purposes. But most importantly you can now actually reproduce them! <\/span><span class=\"r-18u37iz\"><a class=\"css-4rbku5 css-18t94o4 css-901oao css-16my406 r-1cvl2hr r-1loqt21 r-poiln3 r-bcqeeo r-qvutc0\" role=\"link\" href=\"https:\/\/twitter.com\/hashtag\/APTw?src=hashtag_click\">#APTw<\/a><\/span> <span class=\"r-18u37iz\"><a class=\"css-4rbku5 css-18t94o4 css-901oao css-16my406 r-1cvl2hr r-1loqt21 r-poiln3 r-bcqeeo r-qvutc0\" role=\"link\" href=\"https:\/\/twitter.com\/hashtag\/DGE?src=hashtag_click\">#DGE<\/a><\/span> <span class=\"r-18u37iz\"><a class=\"css-4rbku5 css-18t94o4 css-901oao css-16my406 r-1cvl2hr r-1loqt21 r-poiln3 r-bcqeeo r-qvutc0\" role=\"link\" href=\"https:\/\/twitter.com\/hashtag\/GluCEST?src=hashtag_click\">#GluCEST<\/a><\/span> <span class=\"r-18u37iz\"><a class=\"css-4rbku5 css-18t94o4 css-901oao css-16my406 r-1cvl2hr r-1loqt21 r-poiln3 r-bcqeeo r-qvutc0\" role=\"link\" href=\"https:\/\/twitter.com\/hashtag\/MultiPool?src=hashtag_click\">#MultiPool<\/a><\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-510\" src=\"https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pusleq-cest3.png\" alt=\"\" srcset=\"https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pusleq-cest3.png 402w, https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pusleq-cest3-300x190.png 300w, https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pusleq-cest3-378x240.png 378w\" \/><\/p>\n<p><span class=\"css-901oao css-16my406 r-poiln3 r-bcqeeo r-qvutc0\">Moreover, you can simulate these and your own .seq files directly with the builtin Bloch-McConnell simulation in a realistic multi-CEST pool environment. Thus, you can directly compare a novel with an existing CEST sequences in a simulation.<\/span><\/p>\n<p><span class=\"css-901oao css-16my406 r-poiln3 r-bcqeeo r-qvutc0\"> Here for different B0:<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-511\" src=\"https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pusleq-cest4.png\" alt=\"\" srcset=\"https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pusleq-cest4.png 448w, https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pusleq-cest4-300x249.png 300w, https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pusleq-cest4-289x240.png 289w, https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pusleq-cest4-385x320.png 385w\" \/><\/p>\n<p><span class=\"css-901oao css-16my406 r-poiln3 r-bcqeeo r-qvutc0\">(iv) Finally, with a Pulseq interpreter, you can run pulseq-CEST sequences at a real scanner. This includes all saftey and scanner limit checks. Thus, you can go very fast from a new idea to in vivo application. Below CEST-MR fingerprinting in vivo using pulseq-CEST: <\/span><\/p>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-507\" src=\"https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pulseq-cest5.jpg\" alt=\"\" srcset=\"https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pulseq-cest5.jpg 1108w, https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pulseq-cest5-300x139.jpg 300w, https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pulseq-cest5-1024x476.jpg 1024w, https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pulseq-cest5-768x357.jpg 768w, https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pulseq-cest5-480x223.jpg 480w, https:\/\/www.mr-physik.med.fau.de\/files\/2022\/04\/pulseq-cest5-940x437.jpg 940w\" \/><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Do you know about\u00a0Pulseq-CEST? Pulseq-CEST is a CEST RF preparation standard based on Pulseq initiated by AG Zaiss at FAU, UKER and MPI T\u00fcbingen. You can learn more about Pulseq-CEST in a video by Kai Herz from the MRI Together 2021: but also in the original paper https:\/\/doi.org\/10.1002\/mrm.28825 What is pulseq-CEST? First of all, you [&hellip;]<\/p>\n","protected":false},"author":3987,"featured_media":512,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_rrze_cache":"enabled","_rrze_multilang_single_locale":"en_US","_rrze_multilang_single_source":"https:\/\/www.mr-physik.med.fau.de\/?p=503","footnotes":""},"categories":[14,1],"tags":[],"class_list":["post-1661","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ag-zaiss","category-allgemein","en-US"],"_links":{"self":[{"href":"https:\/\/www.mr-physik.med.fau.de\/wp-json\/wp\/v2\/posts\/1661","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.mr-physik.med.fau.de\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.mr-physik.med.fau.de\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.mr-physik.med.fau.de\/wp-json\/wp\/v2\/users\/3987"}],"replies":[{"embeddable":true,"href":"https:\/\/www.mr-physik.med.fau.de\/wp-json\/wp\/v2\/comments?post=1661"}],"version-history":[{"count":3,"href":"https:\/\/www.mr-physik.med.fau.de\/wp-json\/wp\/v2\/posts\/1661\/revisions"}],"predecessor-version":[{"id":1667,"href":"https:\/\/www.mr-physik.med.fau.de\/wp-json\/wp\/v2\/posts\/1661\/revisions\/1667"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.mr-physik.med.fau.de\/wp-json\/wp\/v2\/media\/512"}],"wp:attachment":[{"href":"https:\/\/www.mr-physik.med.fau.de\/wp-json\/wp\/v2\/media?parent=1661"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.mr-physik.med.fau.de\/wp-json\/wp\/v2\/categories?post=1661"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.mr-physik.med.fau.de\/wp-json\/wp\/v2\/tags?post=1661"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}